Search Ontology:
ChEBI
CAN-508
- Term ID
- CHEBI:42356
- Synonyms
-
- 4-[(3,5-diamino-1H-pyrazol-4-yl)diazenyl]phenol
- 4-[2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]phenol
- CAN 508
- CAN508
- CAY 10574
- CAY-10574
- CAY10574
- Cdk9 inhibitor II
- Definition
- A member of the class of pyrazoles that is 1H-pyrazole substituted by amino, (4-hydroxyphenyl)diazenyl, and amino groups at positions 3, 4 and 5, respectively. It is a CDK9 inhibitor (IC50 = 0.35 muM) with 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes.
- References
-
- CAS:140651-18-9
- Chemspider:20487868
- DrugBank:DB07731
- PDBeChem:F18
- PMID:17064068
- PMID:18423896
- PMID:21777997
- PMID:22292676
- PMID:23252711
- PMID:24803299
- PMID:25835357
- PMID:28404924
- PMID:29329219
- PMID:29550093
- PMID:31655429
- PMID:31972394
- PMID:34365958
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from CAN-508
Phenotype where environments contain CAN-508
Phenotype modified by environments containing CAN-508
Human Disease Model