lovastatin

Term ID

CHEBI:40303

Synonyms

• (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate
• (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
• 2beta,6alpha-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone
• 6alpha-methylcompactin
• Lovastatin
• Mevacor
• Mevinolin
• MK-803
• ML-530B

Definition

A fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom).

References

• Beilstein:3631989
• CAS:75330-75-5
• DrugBank:DB00227
• Drug_Central:1612
• HMDB:HMDB0014372
• KEGG:C07074
• KEGG:D00359
• KNApSAcK:C00000547
• LINCS:LSM-2189
• PDBeChem:803
• PMID:11375168
• PMID:11389707
• PMID:11483865
• PMID:18642339
• PMID:24093797
• PMID:7720768
• Patent:CN103172602
• Patent:WO2013090461
• Reaxys:4720754
• Wikipedia:Lovastatin

Ontology

ChEBI  ( EBI )

Resources

CTD