timolol

Term ID

CHEBI:39465

Synonyms

1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

Definition

1,2,5-Thiadiazole substituted at the 3 position by a 3-(tert-butylamino)-2-hydroxypropoxy group and at the 4 position by a morpholin-4-yl group. The (S)-(-) enantiomer, also known as timolol, is a beta-adrenergic antagonist and is used in the mangement of glaucoma, hypertension, angina pectoris and myocardial infarction, and for the prevention of migraine.

References

Beilstein:555286
DrugBank:DB00373
HMDB:HMDB0014517
LINCS:LSM-4397

Ontology

ChEBI ( EBI )

Relationships

is a type of: morpholines thiadiazoles

morpholines thiadiazoles Show first 5 Terms
has subtype: (R)-timolol (S)-timolol (anhydrous)

(R)-timolol (S)-timolol (anhydrous) Show first 5 Terms
has_parent_hydride: 1,2,5-thiadiazole

1,2,5-thiadiazole Show first 5 Terms

Phenotype

Phenotype resulting from timolol

Phenotype where environments contain timolol

Phenotype modified by environments containing timolol

Human Disease Model