Search Ontology:
ChEBI
dizocilpine
- Term ID
- CHEBI:34725
- Synonyms
-
- (+)-dizocilpine
- (+)-MK-801
- (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene
- dizocilpina
- dizocilpine
- dizocilpinum
- MK 801
- MK-801
- MK801
- Definition
- An organic heterotetracyclic compound that is 1-methyl-8-azabicyclo[3.2.1]octane ortho-fused to two benzene rings at positions 2-3 and 6-7 (the 5S,10R-stereoisomer). It is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and affects cognitive function, learning, and memory.
- References
-
- CAS:77086-21-6
- Chemspider:156718
- KEGG:C13737
- LINCS:LSM-5688
- PDBeChem:BMK
- PMID:28232581
- PMID:29489358
- PMID:29670280
- PMID:30772438
- PMID:31177060
- PMID:32105720
- PMID:32219769
- PMID:32289529
- PMID:32324160
- PMID:32641944
- PMID:32760846
- PMID:32808583
- PMID:32892308
- PMID:32956214
- PMID:32973585
- PMID:33187817
- PMID:33249825
- PMID:33324181
- PMID:33404734
- PMID:33442771
- PMID:33639267
- PMID:33656787
- PMID:33723767
- PMID:33809889
- PMID:33882624
- PMID:33891976
- PMID:33945878
- PMID:33974921
- PMID:34054433
- PMID:34098454
- PMID:34119597
- PMID:34177484
- Wikipedia:Dizocilpine
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
- inverse is_conjugate_acid_of
-
- is_conjugate_base_of
-
Phenotype
Phenotype resulting from dizocilpine
Phenotype where environments contain dizocilpine
Phenotype modified by environments containing dizocilpine
Human Disease Model