Search Ontology:
ChEBI
butenafine
- Term ID
- CHEBI:3238
- Synonyms
-
- (4-tert-Butyl-benzyl)-methyl-naphthalen-1-ylmethyl-amine
- (4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine
- 1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine
- 4-tert-butylbenzyl(methyl)(1-naphthalenemethyl)amine
- butenafina
- Butenafine
- butenafinum
- N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamine
- Definition
- Trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is an inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes, and is used as its hydrochloride salt for treatment of dermatological fungal infections.
- References
-
- Beilstein:6334654
- CAS:101828-21-1
- DrugBank:DB01091
- Drug_Central:444
- KEGG:C08067
- KEGG:D07596
- LINCS:LSM-5956
- PMID:17371821
- PMID:8340915
- Patent:EP164697
- Patent:US5021458
- Wikipedia:Butenafine
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_role
-
- inverse has_part
-
Phenotype
Phenotype resulting from butenafine
Phenotype where environments contain butenafine
Phenotype modified by environments containing butenafine
Human Disease / Model Data