Search Ontology:
ChEBI

nemonapride

Term ID
CHEBI:31899
Synonyms
  • (+-)-cis-N-(1-benzyl-2-methyl-3-pyrrolidinyl)-5-chloro-4-(methylamino)-o-anisamide
  • (+-)-cis-N-(1-benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylaminobenzamide
  • (+-)-nemonapride
  • Emilace
  • emonapride
  • nemonaprida
  • nemonapride
  • nemonapridum
  • rac-N-[(2S,3S)-1-benzyl-2-methylpyrrolidin-3-yl]-5-chloro-2-methoxy-4-(methylamino)benzamide
  • rac-nemonapride
  • racemic nemonapride
  • YM 09151-2
  • YM-09151
(all 13)
Definition
A racemate composed of (2S,3S)- and (2R,3R)-enantiomers of nemonapride. Highly potent dopamine D2-like receptor antagonist; selective over D1-like receptors (Ki values are 0.1 and 740 nM for D2-like and D1-like receptors respectively). Also potent 5-HT1A receptor agonist (IC50 = 34 nM) and has affinity for sigma receptors.
References
(all 30)
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_part
has_role
Phenotype
Phenotype resulting from nemonapride
No data available
Phenotype where environments contain nemonapride
No data available
Phenotype modified by environments containing nemonapride
No data available
Human Disease Model
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