Search Ontology:
ChEBI
nemonapride
- Term ID
- CHEBI:31899
- Synonyms
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- (+-)-cis-N-(1-benzyl-2-methyl-3-pyrrolidinyl)-5-chloro-4-(methylamino)-o-anisamide
- (+-)-cis-N-(1-benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylaminobenzamide
- (+-)-nemonapride
- Emilace
- emonapride
- nemonaprida
- nemonapride
- nemonapridum
- rac-N-[(2S,3S)-1-benzyl-2-methylpyrrolidin-3-yl]-5-chloro-2-methoxy-4-(methylamino)benzamide
- rac-nemonapride
- racemic nemonapride
- YM 09151-2
- YM-09151
- Definition
- A racemate composed of (2S,3S)- and (2R,3R)-enantiomers of nemonapride. Highly potent dopamine D2-like receptor antagonist; selective over D1-like receptors (Ki values are 0.1 and 740 nM for D2-like and D1-like receptors respectively). Also potent 5-HT1A receptor agonist (IC50 = 34 nM) and has affinity for sigma receptors.
- References
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- CAS:75272-39-8
- Drug_Central:1895
- KEGG:C12915
- KEGG:D01468
- PMID:10049714
- PMID:10363800
- PMID:10435376
- PMID:10587100
- PMID:10823405
- PMID:10862524
- PMID:10898926
- PMID:10917400
- PMID:11817505
- PMID:11929700
- PMID:16020947
- PMID:8328325
- PMID:9016292
- PMID:9031995
- PMID:9095318
- PMID:9228185
- PMID:9310388
- PMID:9325557
- PMID:9369342
- PMID:9766869
- PMID:9774248
- PMID:9934942
- Patent:EP1273301
- Patent:US5811547
- Reaxys:5766104
- Wikipedia:Nemonapride
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_part
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- has_role
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Show first 5 Terms
Phenotype
Phenotype resulting from nemonapride
Phenotype where environments contain nemonapride
Phenotype modified by environments containing nemonapride
Human Disease Model