Search Ontology:
ChEBI
lopinavir
- Term ID
- CHEBI:31781
- Synonyms
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- (2S)-N-[(2S,4S,5S)-5-{[(2,6-dimethylphenoxy)acetyl]amino}-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
- Lopinavir
- Definition
- A dicarboxylic acid diamide that is amphetamine is substituted on nitrogen by a (2,6-dimethylphenoxy)acetyl group and on the carbon alpha- to nitrogen by a (1S,3S)-1-hydroxy-3-{[(2S)-3-methyl-2-(2-oxotetrahydropyrimidin-1-yl)butanoyl]amino}-4-phenylbutyl group. An antiretroviral of the protease inhibitor class, it is used against HIV infections as a fixed-dose combination with another protease inhibitor, ritonavir.
- References
-
- CAS:192725-17-0
- DrugBank:DB01601
- Drug_Central:1601
- HMDB:HMDB0015539
- KEGG:C12871
- KEGG:D01425
- LINCS:LSM-6027
- PDBeChem:AB1
- PMID:24014186
- PMID:24518130
- PMID:24566184
- PMID:24805184
- PMID:24906762
- PMID:24958908
- PMID:25120613
- Reaxys:9309881
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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- inverse has_part
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Phenotype
Phenotype resulting from lopinavir
Phenotype where environments contain lopinavir
Phenotype modified by environments containing lopinavir
Human Disease Model