Search Ontology:
ChEBI
neocarzinostatin chromophore
- Term ID
- CHEBI:29655
- Synonyms
-
- (1aS,5R,6R,6aE,9aR)-6-{[2,6-dideoxy-2-(methylamino)-alpha-D-galactopyranosyl]oxy}-1a-[(4R)-2-oxo-1,3-dioxolan-4-yl]-2,3,8,9-tetradehydro-1a,5,6,9a-tetrahydrocyclopenta[5,6]cyclonona[1,2-b]oxiren-5-yl 2-hydroxy-7-methoxy-5-methyl-1-naphthoate
- Ncs-chrom
- Neocarzinostatin chromophore
- Definition
- A naphthoate ester obtained by formal condensation of the carboxy group of 2-hydroxy-7-methoxy-5-methyl-1-naphthoic acid with the 5-hydroxy group of (1aS,5R,6R,6aE,9aR)-5-hydroxy-1a-[(4R)-2-oxo-1,3-dioxolan-4-yl]-2,3,8,9-tetradehydro-1a,5,6,9a-tetrahydrocyclopenta[5,6]cyclonona[1,2-b]oxiren-6-yl 2,6-dideoxy-2-(methylamino)-alpha-D-galactopyranoside. The chromophoric part of neocarzinostatin, it is tightly and non-covelently bound to a 113-membered apoprotein, which serves to protect it and release it to the target DNA.
- References
-
- CAS:81604-85-5
- Drug_Central:4108
- KEGG:C12049
- PDBeChem:CHR
- PMID:11735421
- PMID:11916399
- PMID:11955061
- PMID:16546380
- PMID:20336247
- PMID:20735485
- PMID:2524463
- PMID:2976601
- PMID:6220205
- PMID:6223633
- PMID:7582949
- PMID:7582957
- PMID:8362243
- PMID:8466903
- Reaxys:4224827
- Wikipedia:Neocarzinostatin
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from neocarzinostatin chromophore
Phenotype where environments contain neocarzinostatin chromophore
Phenotype modified by environments containing neocarzinostatin chromophore
Human Disease / Model Data