Search Ontology:
ChEBI
desloratadine
- Term ID
- CHEBI:291342
- Synonyms
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- 8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
- 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
- 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
- descarboethoxyloratadine
- desloratadine
- Definition
- Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness.
- References
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- Beilstein:4263164
- CAS:100643-71-8
- DrugBank:DB00967
- Drug_Central:814
- KEGG:D03693
- LINCS:LSM-5887
- PMID:11844681
- PMID:15482930
- PMID:9934454
- Patent:EP208855
- Patent:US4659716
- Wikipedia:Desloratadine
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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- inverse has_functional_parent
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Phenotype
Phenotype resulting from desloratadine
Phenotype where environments contain desloratadine
Phenotype modified by environments containing desloratadine
Human Disease / Model Data