21-deoxycortisol

Term ID

CHEBI:28697

Synonyms

• (1R,3aS,3bS,9aR,9bS,10S,11aS)-1-acetyl-1,10-dihydroxy-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one
• 11-beta,17-alpha-dihydroxypregn-4-ene-3,20-dione
• 11beta,17-dihydroxypregn-4-ene-3,20-dione
• 11beta,17-dihydroxyprogesterone
• 11beta,17alpha-dihydroxypregn-4-ene-3,20-dione
• 11beta,17alpha-dihydroxyprogesterone
• 21-deoxycortisol
• 4-pregnene-11beta,17alpha-diol-3,20-dione
• pregn-4-ene-11beta,17alpha-diol-3,20-dione

Definition

A deoxycortisol that is 17xi-pregn-4-ene-3,20-dione substituted by a beta-hydroxy group at position 11 and an alpha-hydroxy group at position 17. It is a marker of virilizing adrenal hyperplasia caused by 21-hydroxylase deficiency.

References

• CAS:641-77-0
• FooDB:FDB023283
• HMDB:HMDB0004030
• KEGG:C05497
• LIPID_MAPS_instance:LMST02030195
• PMID:10731638
• PMID:16551734
• PMID:17456574
• PMID:2531882
• PMID:2555382
• PMID:2614011
• PMID:2827419
• PMID:28499151
• PMID:28610588
• PMID:28774496
• PMID:2986404
• PMID:31450227
• PMID:3258316
• PMID:4372245
• PMID:6310249
• PMID:8055790
• PMID:845476
• PMID:8753277
• Wikipedia:21-Deoxycortisol

Ontology

ChEBI  ( EBI )

Resources

CTD