Search Ontology:
ChEBI

cisplatin

Term ID
CHEBI:27899
Synonyms
  • (SP-4-2)-diamminedichloridoplatinum
  • (SP-4-2)-diamminedichloroplatinum
  • [PtCl2(NH3)2]
  • Briplatin
  • CDDP
  • cis-[PtCl2(NH3)2]
  • cis-DDP
  • cis-diamminedichloridoplatinum(II)
  • cis-diamminedichloroplatinum
  • cis-Diamminedichloroplatinum(II)
  • cis-diammineplatinum(II) dichloride
  • cis-dichlorodiammineplatinum(II)
  • cis-platin
  • Cismaplat
  • cisplatin
  • cisplatine
  • cisplatino
  • cisplatinum
  • Lederplatin
  • Neoplatin
  • Peyrone's chloride
  • Peyrone's salt
  • Platamine
  • Platinex
  • Platinol
  • Randa
Definition
A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups).
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from cisplatin
Phenotype where environments contain cisplatin
Phenotype modified by environments containing cisplatin
Human Disease / Model Data