Search Ontology:
ChEBI

aldosterone

Term ID
CHEBI:27584
Synonyms
  • (+)-aldosterone
  • (11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al
  • 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al
  • 11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al
  • ALDOSTERONE
Definition
A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.
References
  • CAS:52-39-1
  • DrugBank:DB04630
  • Drug_Central:111
  • HMDB:HMDB0000037
  • KEGG:C01780
  • LINCS:LSM-42770
  • LIPID_MAPS_instance:LMST02030026
  • PDBeChem:AS4
  • PMID:10438974
  • Reaxys:3224996
  • Wikipedia:Aldosterone
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_parent_hydride
has_role
inverse has_functional_parent
Phenotype
Phenotype resulting from aldosterone
Phenotype where environments contain aldosterone
Phenotype modified by environments containing aldosterone
Human Disease Model