Search Ontology:
ChEBI

GSK046

Term ID
CHEBI:231669
Synonyms
  • 4-acetamido-3-fluoro-N-((1R,4S)-4-hydroxycyclohexyl)-5-((S)-1-phenylethoxy)benzamide
  • 4-acetamido-3-fluoro-N-(trans-4-hydroxycyclohexyl)-5-[(1S)-1-phenylethoxy]benzamide
  • 4-acetamido-3-fluoro-N-[(1r,4S)-4-hydroxycyclohexyl]-5-[(1S)-1-phenylethoxy]benzamide
  • GSK 046
  • GSK-046
  • iBET-BD2
Definition
A secondary carboxamide resulting from the formal condensation of the carboxy group of 4-acetamido-3-fluoro-5-[(1S)-1-phenylethoxy]benzoic acid with the amino group of trans-4-aminocyclohexanol. It is a potent pan-BD2 bromodomain inhibitor.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from GSK046
Phenotype where environments contain GSK046
Phenotype modified by environments containing GSK046
Human Disease Model
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