Search Ontology:
ChEBI
SH-1280
- Term ID
- CHEBI:231662
- Synonyms
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- (2S)-2-(3,4-dimethoxyphenyl)-1-(5-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)propan-1-one
- (2S)-2-(3,4-dimethoxyphenyl)-1-(5-methoxy-2,2-dimethyl-2H-chromen-6-yl)propan-1-one
- SH 1280
- SH1280
- Definition
- A chromene that is 2,2-dimethyl-2H-chromene substituted by methoxy and (2S)-2-(3,4-dimethoxyphenyl)propanoyl groups at positions 5 and 6, respectively. It is a Hsp90 inhibitor that prevents hypoxia-mediated retinal neovascularization and could potentially be used as a treatment for diabetic retinopathy.
- References
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_role
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Phenotype
Phenotype resulting from SH-1280
Phenotype where environments contain SH-1280
Phenotype modified by environments containing SH-1280
Human Disease Model