Search Ontology:
ChEBI

BAY 73-6691

Term ID
CHEBI:231440
Synonyms
  • (R)-BAY 73-6691
  • (R)-BAY-73-6691
  • 1-(2-chlorophenyl)-1,5-dihydro-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-4H-pyrazolo[3,4-d]pyrimidin-4-one
  • 1-(2-chlorophenyl)-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
  • BAY 736691
  • BAY-73-6691
  • BAY736691
Definition
A member of the class of pyrazolopyrimidines that is 4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidine substituted by 2-chlorophenyl, oxo, and (2R)-3,3,3-trifluoro-2-methylpropyl groups at positions 1, 4 and 6, respectively. It is a potent and selective inhibitor of phosphodiesterase 9 (PDE9), currently in pre-clinical development for the treatment of Alzheimer's disease.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from BAY 73-6691
Phenotype where environments contain BAY 73-6691
Phenotype modified by environments containing BAY 73-6691
Human Disease Model