Search Ontology:
ChEBI
LDN-212854
- Term ID
- CHEBI:229962
- Synonyms
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- 5-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
- 5-{6-[4-(piperazin-1-yl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl}quinoline
- LDN 212854
- LDN212854
- Definition
- A member of the class of quinolines that is quinoline substituted by a 6-[4-(piperazin-1-yl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl group at position 5. It is a potent ALK inhibitor (IC50 values of 2.4, 1.3, 85.8, 2,133 and 9,276 nM for ALK1, ALK2, ALK3, ALK4 and ALK5, respectively).
- References
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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Show first 5 Terms
Phenotype
Phenotype resulting from LDN-212854
Phenotype where environments contain LDN-212854
Phenotype modified by environments containing LDN-212854
Human Disease Model