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ChEBI

TA-1887

Term ID
CHEBI:229237
Synonyms
  • (2R,3R,4S,5S,6R)-2-[3-(4-cyclopropylbenzyl)-4-fluoro-1H-indol-1-yl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • (2R,3R,4S,5S,6R)-2-[3-[(4-cyclopropylphenyl)methyl]-4-fluoranyl-indol-1-yl]-6-(hydroxymethyl)oxane-3,4,5-triol
  • 3-(4-cyclopropylbenzyl)-4-fluoro-1-beta-D-glucopyranosyl-1H-indole
  • 3-(4-cyclopropylbenzyl)-4-fluoroindole-N-glucoside
  • 3-[(4-cyclopropylphenyl)methyl]-4-fluoro-1-beta-D-glucopyranosyl-1H-indole
  • JNJ 39933673
  • JNJ-39933673
  • JNJ39933673
  • TA 1887
  • TA1887
Definition
A fluoroindole that is 1H-indole substituted by a beta-D-glucopyranosyl, 4-cyclopropylbenzyl, and fluoro groups at positions 1, 3 and 4, respectively. It is a highly potent and selective SGLT2 inhibitor, with antihyperglycemic effects in high-fat diet-fed KK mice.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from TA-1887
Phenotype where environments contain TA-1887
Phenotype modified by environments containing TA-1887
Human Disease / Model Data