TA-1887

Term ID

CHEBI:229237

Synonyms

(2R,3R,4S,5S,6R)-2-[3-(4-cyclopropylbenzyl)-4-fluoro-1H-indol-1-yl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
(2R,3R,4S,5S,6R)-2-[3-[(4-cyclopropylphenyl)methyl]-4-fluoranyl-indol-1-yl]-6-(hydroxymethyl)oxane-3,4,5-triol
3-(4-cyclopropylbenzyl)-4-fluoro-1-beta-D-glucopyranosyl-1H-indole
3-(4-cyclopropylbenzyl)-4-fluoroindole-N-glucoside
3-[(4-cyclopropylphenyl)methyl]-4-fluoro-1-beta-D-glucopyranosyl-1H-indole
JNJ 39933673
JNJ-39933673
JNJ39933673
TA 1887
TA1887

Definition

A fluoroindole that is 1H-indole substituted by a beta-D-glucopyranosyl, 4-cyclopropylbenzyl, and fluoro groups at positions 1, 3 and 4, respectively. It is a highly potent and selective SGLT2 inhibitor, with antihyperglycemic effects in high-fat diet-fed KK mice.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: benzenes cyclopropanes fluoroindole N-glycosyl compound

benzenes cyclopropanes fluoroindole N-glycosyl compound Show first 5 Terms
has_role: hypoglycemic agent sodium-glucose transport protein subtype 2 inhibitor

hypoglycemic agent sodium-glucose transport protein subtype 2 inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from TA-1887

Phenotype where environments contain TA-1887

Phenotype modified by environments containing TA-1887

Human Disease / Model Data