Search Ontology:
ChEBI

zuranolone

Term ID
CHEBI:228302
Synonyms
  • 1-(3alpha-hydroxy-3beta-methyl-20-oxo-5beta-19-norpregnan-21-yl)-1H-pyrazole-4-carbonitrile
  • 1-[(3alpha,5beta)-3-hydroxy-3-methyl-20-oxo-19-norpregnan-21-yl]-1H-pyrazole-4-carbonitrile
  • BIIB-125
  • BIIB125
  • S-812217
  • SAGE 217
  • SAGE-217
  • SAGE217
  • SGE 797
  • SGE-797
  • zuranolone
  • zuranolonum
  • Zurzuvae
Definition
A 3-hydroxy steroid that is 5beta-19-norpregnane substituted by hydroxy, methyl, oxo, and 4-cyano-1H-pyrazol-1-yl groups at positions 3, 3, 20 and 21, respectively. It is a positive allosteric modulator of GABAA receptor developed by Sage Therapeutics and Biogen for the treatment of postpartum depression in adults.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from zuranolone
Phenotype where environments contain zuranolone
Phenotype modified by environments containing zuranolone
Human Disease Model
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