Search Ontology:
ChEBI

mocetinostat

Term ID
CHEBI:197437
Synonyms
  • MG 0103
  • MGCD 0103
  • MGCD-0103
  • MGCD0103
  • mocetinostat
  • mocetinostatum
  • N-(2-aminophenyl)-4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzamide
  • N-(2-aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]benzamide
Definition
A benzamide obtained by formal condensation of the carboxy group of 4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an orally active and isotype-selective HDAC inhibitor which exhibits antitumour activity (IC50 = 0.15, 0.29, 1.66 and 0.59 muM for HDAC1, HDAC2, HDAC3 and HDAC11).
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from mocetinostat
Phenotype where environments contain mocetinostat
Phenotype modified by environments containing mocetinostat
Human Disease Model
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