ML355

Term ID

CHEBI:195557

Synonyms

ML 355
ML-355
N-(1,3-benzothiazol-2-yl)-4-[(2-hydroxy-3-methoxybenzyl)amino]benzenesulfonamide
N-(1,3-benzothiazol-2-yl)-4-{[(2-hydroxy-3-methoxyphenyl)methyl]amino}benzene-1-sulfonamide
VLX 1005
VLX-1005
VLX1005

Definition

A sulfonamide resulting from the formal condensation of the amino group of 2-aminobenzothiazole with the sulfo group of 4-[(2-hydroxy-3-methoxybenzyl)amino]benzenesulfonic acid. It is an inhibitor of 12-lipoxygenase, being developed by Veralox Therapeutics for the treatment of heparin-induced thrombocytopenia and thrombosis.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: benzothiazoles monomethoxybenzene phenols secondary amino compound substituted aniline ... Show All 6 Terms

benzothiazoles monomethoxybenzene phenols secondary amino compound substituted aniline sulfonamide Show first 5 Terms
has_functional_parent: 2-aminobenzothiazole

2-aminobenzothiazole Show first 5 Terms
has_role: EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor platelet aggregation inhibitor

EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor platelet aggregation inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from ML355

Phenotype where environments contain ML355

Phenotype modified by environments containing ML355

Human Disease / Model Data