Search Ontology:
ChEBI

numidargistat

Term ID
CHEBI:195556
Synonyms
  • (3R,4S)-1-L-alanyl-3-amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic acid
  • (3R,4S)-3-amino-1-[(2S)-2-aminopropanoyl]-4-(3-boronopropyl)pyrrolidine-3-carboxylic acid
  • CB 1158
  • CB-1158
  • CB1158
  • INCB 001158
  • INCB-001158
  • INCB001158
  • numidargistat
  • numidargistatum
Definition
An aminopyrrolidine that is pyrrolidine substituted by (2S)-2-aminopropanoyl, amino, carboxy, and 3-boronopropyl groups at positions 1, 3, 3, and 4 (the 3R,4S-stereoisomer). It is a selective arginase inhibitor being developed by Calithera Biosciences for the treatment of solid tumours.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from numidargistat
Phenotype where environments contain numidargistat
Phenotype modified by environments containing numidargistat
Human Disease Model
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