Search Ontology:
ChEBI
lobaplatin
- Term ID
- CHEBI:192744
- Synonyms
-
- 1,2-diamino-methylcyclobutane platinum(II) lactate
- 1,2-diamino-methylcyclobutane-platinum(II) lactate
- [2-hydroxypropanoato(2-)-O1,O2][1,2-cyclobutanedimethanamine-N,N']platinum(II)
- D 19466
- D-19466
- D19466
- lobaplatin
- lobaplatine
- lobaplatino
- lobaplatinum
- Definition
- A 1:1 diastereomeric mixture comprising of R,R,S and S,S,S configuration of platinum(II) complexes with 1,2-bis(aminomethyl)cyclobutane as the carrier ligand and lactate as the leaving group. It is a third-generation platinum anticancer drug approved in China for the treatment of chronic myelogenous leukaemia, inoperable metastatic breast cancer and small cell lung cancer.
- References
-
- CAS:135558-11-1
- DrugBank:DB13049
- PMCID:PMC7750111
- PMID:14584968
- PMID:2229133
- PMID:25516654
- PMID:31876741
- PMID:32413426
- PMID:32582992
- PMID:32636676
- PMID:33262658
- PMID:33469307
- PMID:33613708
- PMID:33791202
- PMID:34282830
- PMID:34306603
- PMID:34430592
- PMID:34589419
- PMID:34666646
- PMID:34746003
- PMID:34837558
- PMID:34853650
- PMID:35025294
- PMID:35164703
- PMID:35211587
- PMID:35575667
- PMID:35648285
- PMID:35652401
- PMID:35719323
- PMID:35722417
- PMID:35769355
- PMID:35794989
- PMID:36119883
- PMID:36186198
- PMID:36221355
- PMID:36247269
- PMID:36330235
- PMID:36626436
- PMID:36714400
- PMID:36727741
- PMID:36741012
- Wikipedia:Lobaplatin
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_part
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- has_role
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Phenotype
Phenotype resulting from lobaplatin
Phenotype where environments contain lobaplatin
Phenotype modified by environments containing lobaplatin
Human Disease / Model Data