Search Ontology:
ChEBI

lobaplatin

Term ID
CHEBI:192744
Synonyms
  • 1,2-diamino-methylcyclobutane platinum(II) lactate
  • 1,2-diamino-methylcyclobutane-platinum(II) lactate
  • [2-hydroxypropanoato(2-)-O1,O2][1,2-cyclobutanedimethanamine-N,N']platinum(II)
  • D 19466
  • D-19466
  • D19466
  • lobaplatin
  • lobaplatine
  • lobaplatino
  • lobaplatinum
Definition
A 1:1 diastereomeric mixture comprising of R,R,S and S,S,S configuration of platinum(II) complexes with 1,2-bis(aminomethyl)cyclobutane as the carrier ligand and lactate as the leaving group. It is a third-generation platinum anticancer drug approved in China for the treatment of chronic myelogenous leukaemia, inoperable metastatic breast cancer and small cell lung cancer.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_part
has_role
Phenotype
Phenotype resulting from lobaplatin
Phenotype where environments contain lobaplatin
Phenotype modified by environments containing lobaplatin
Human Disease / Model Data