Search Ontology:
ChEBI

LY 379268

Term ID
CHEBI:192545
Synonyms
  • (1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid
  • LY-379,268
  • LY-379268
  • LY379268
(all 4)
Definition
An organic heterobicyclic compound that is (1R,5S)-2-oxabicyclo[3.1.0]hexane carrying amino, carboxy, and carboxy groups at positions 4R, 4R and 6R, respectively. It is a potent agonist of group II metabotropic glutamate receptors mGluR2 and mGluR3 (EC50 = 2.69 nM and 4.48 nM, respectively) that exhibits antipsychotic-like action in animal models of schizophrenia.
References
(all 36)
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from LY 379268
No data available
Phenotype where environments contain LY 379268
No data available
Phenotype modified by environments containing LY 379268
No data available
Human Disease Model
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