varespladib

Term ID

CHEBI:189668

Synonyms

({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid
2-[2-ethyl-3-oxamoyl-1-(phenylmethyl)indol-4-yl]oxyethanoic acid
2-[[3-(2-Amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetic acid
A-001
LY 315920
LY-315920
LY315920
S 5920
S-5920
varespladib
varespladibum

(all 11)

Definition

A member of the class of indoles that is 1H-indole substituted by benzyl, ethyl, oxamoyl, and carboxymethoxy groups at positions 1, 2, 3, and 4, respectively. It is an oral secretory phospholipase A2 inhibitor and exhibits anti-inflammatory effects.

References

(all 36)

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether benzenes dicarboxylic acid monoamide indoles monocarboxylic acid ... Show All 6 Terms

aromatic ether benzenes dicarboxylic acid monoamide indoles monocarboxylic acid primary carboxamide Show first 5 Terms
has_role: anti-inflammatory drug antidote EC 3.1.1.4 (phospholipase A2) inhibitor

anti-inflammatory drug antidote EC 3.1.1.4 (phospholipase A2) inhibitor Show first 5 Terms
inverse has_functional_parent: varespladib methyl

varespladib methyl Show first 5 Terms
inverse is_conjugate_base_of: varespladib(1-)

varespladib(1-) Show first 5 Terms
is_conjugate_acid_of: varespladib(1-)

varespladib(1-) Show first 5 Terms

Phenotype

Phenotype resulting from varespladib

Phenotype where environments contain varespladib

Phenotype modified by environments containing varespladib

Human Disease Model