Search Ontology:
ChEBI
alpha-Neu5Ac-(2->3)-beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer
- Term ID
- CHEBI:189546
- Synonyms
-
- alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-ceramide
- NeuAcalpha2-3Galbeta1-3GalNAcbeta1-3Galalpha1-4Galbeta1-4Glcbeta-Cer
- NeuAcalpha2->3Galbeta1->3GalNAcbeta1->3Galalpha1->4Galbeta1->4Glcbeta1->1Cer
- SSEA-4
- SSEA-4 antigen
- SSEA4
- stage-specific embryonic antigen 4
- stage-specific embryonic antigen-4
- Definition
- A glycotetraosylceramide having N-acetyl-beta-D-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucose as the hexasaccharide component. It is overexpressed in some cancers and has been linked to disease progression.
- References
-
- KEGG:G00098
- LIPID_MAPS_instance:LMSP0601AB00
- MetaCyc:SSEA4
- PMID:1979319
- PMID:20683402
- PMID:22237379
- PMID:22266579
- PMID:22743677
- PMID:23301556
- PMID:23515456
- PMID:24279891
- PMID:24550271
- PMID:24581260
- PMID:25978997
- PMID:26607327
- PMID:27797400
- PMID:27836003
- PMID:28736232
- PMID:29907955
- PMID:31243630
- PMID:31831622
- PMID:31916611
- PMID:32691968
- PMID:32988880
- PMID:33733429
- PMID:33945505
- PMID:34211078
- PMID:34230128
- PMID:34369155
- PMID:34667379
- PMID:34734786
- PMID:34876527
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
- inverse is_conjugate_base_of
-
- is_conjugate_acid_of
-
Show first 5 Terms
Phenotype
Phenotype resulting from alpha-Neu5Ac-(2->3)-beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer
Phenotype where environments contain alpha-Neu5Ac-(2->3)-beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer
Phenotype modified by environments containing alpha-Neu5Ac-(2->3)-beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer
Human Disease Model