Search Ontology:
ChEBI
2,8-dihydroxyadenine
- Term ID
- CHEBI:183641
- Synonyms
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- 2,8-DHA
- 6-amino-2,8-dihydroxypurine
- 6-amino-9H-purine-2,8-diol
- 6-amino-purine-2,8-diol
- Definition
- A member of the class of 6-aminopurines that is adenine bearing two hydroxy substituents at positions 2 and 8. It is a highly insoluble metabolite of adenine that causes radiolucent urolithiasis. It is produced by individuals who suffer from adenine phosphoribosyltransferase (APRT) deficiency, a rare autosomal recessive error of purine metabolism.
- References
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- CAS:30377-37-8
- FooDB:FDB022018
- HMDB:HMDB0000401
- PMID:10481956
- PMID:15025810
- PMID:16713382
- PMID:20098761
- PMID:21553389
- PMID:23113528
- PMID:24359665
- PMID:24940675
- PMID:25307253
- PMID:26278213
- PMID:27447713
- PMID:27770717
- PMID:28466077
- PMID:28566603
- PMID:28717278
- PMID:29657221
- PMID:29861153
- PMID:30355577
- PMID:31378568
- PMID:31880754
- PMID:32086278
- PMID:32260098
- PMID:32399606
- PMID:32859011
- PMID:33273797
- PMID:33678741
- PMID:34044400
- PMID:34341261
- PMID:34610707
- Wikipedia:2,8-Dihydroxyadenine
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
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- has_functional_parent
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- has_role
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- inverse is_tautomer_of
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- is_tautomer_of
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Phenotype
Phenotype resulting from 2,8-dihydroxyadenine
Phenotype where environments contain 2,8-dihydroxyadenine
Phenotype modified by environments containing 2,8-dihydroxyadenine
Human Disease / Model Data