calcitriol

Term ID

CHEBI:17823

Synonyms

• (1alpha,3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
• (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
• (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol
• (5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
• 1,25-DHCC
• 1-alpha-25-Dihydroxyvitamin D3
• 1alpha,25(OH)2D3
• 1alpha,25-dihydroxycholecalciferol
• 1alpha,25-dihydroxyvitamin D3
• 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL
• Calcijex
• calcitriol
• calcitriolum
• Decostriol
• Rocaltrol

Definition

A hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol.

References

• CAS:32222-06-3
• DrugBank:DB00136
• Drug_Central:466
• KEGG:C01673
• KEGG:D00129
• LIPID_MAPS_instance:LMST03020258
• MetaCyc:CALCITRIOL
• PDBeChem:VDX
• PMID:10217585
• PMID:15928596
• PMID:19429426
• PMID:20599255
• PMID:22905919
• PMID:23103122
• PMID:23144765
• PMID:6687801
• Reaxys:2227647
• Wikipedia:Calcitriol

Ontology

ChEBI  ( EBI )

Resources

CTD