Search Ontology:
ChEBI

2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide

Term ID
CHEBI:177299
Synonyms
  • (R)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide
  • 2-[4-(3R)-3-piperidinylphenyl]-2H-indazole-7-carboxamide
  • 2-[4-[(3R)-piperidin-3-yl]phenyl]indazole-7-carboxamide
  • 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
  • ent-niraparib
  • MK-4827 (R-enantiomer)
  • niraparib (R-enantiomer)
Definition
A 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has R-configuration. It is a potent PARP1 inhibitor with IC50 of 2.4 nM.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
Phenotype where environments contain 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
Phenotype modified by environments containing 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
Human Disease Model
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