Search Ontology:
ChEBI
ML-210
- Term ID
- CHEBI:176502
- Synonyms
-
- [4-[bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)-methanone
- DPI10
- ML 210
- ML210
- {4-[bis(4-chlorophenyl)methyl]piperazin-1-yl}(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone
- Definition
- An N-acylpiperazine that is piperazine substituted by 5-methyl-4-nitro-1,2-oxazole-3-carbonyl and bis(4-chlorophenyl)methyl groups at positions 1 and 4, respectively. It is a glutathione peroxidase 4 (GPX4) inhibitor which induces ferroptosis in cancer cells expressing the RAS oncogene.
- References
-
- CAS:1360705-96-9
- Chemspider:28495222
- LINCS:LSM-2013
- PMID:22297109
- PMID:22834036
- PMID:32080622
- PMID:32231343
- PMID:33741422
- Patent:US20200138829
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Phenotype
Phenotype resulting from ML-210
Phenotype where environments contain ML-210
Phenotype modified by environments containing ML-210
Human Disease / Model Data