Search Ontology:
ChEBI
gemcitabine
- Term ID
- CHEBI:175901
- Synonyms
-
- 2',2'-Difluorodeoxycytidine
- 2'-Deoxy-2',2'-difluorocytidine
- 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
- gemcitabina
- gemcitabine
- gemcitabinum
- Definition
- A 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer.
- References
-
- Beilstein:5382060
- CAS:95058-81-4
- DrugBank:DB00441
- Drug_Central:1283
- KEGG:C07650
- KEGG:D02368
- LINCS:LSM-5333
- PDBeChem:GEO
- PMID:11034044
- PMID:11061612
- PMID:11088063
- PMID:11122828
- PMID:11132538
- PMID:11142482
- PMID:11221019
- PMID:11356111
- PMID:11374818
- PMID:11489002
- PMID:11504793
- PMID:11510027
- PMID:11585734
- PMID:11595724
- PMID:11807603
- PMID:11859947
- PMID:11901308
- PMID:12057041
- PMID:12057046
- PMID:12057157
- PMID:12115355
- PMID:12142097
- PMID:12520460
- PMID:12571808
- PMID:12722678
- PMID:12722691
- PMID:12743987
- PMID:12761494
- PMID:12798170
- PMID:12917815
- PMID:12954073
- PMID:14606642
- PMID:14653877
- PMID:14720338
- PMID:15131028
- PMID:15160243
- PMID:15221904
- PMID:15282439
- PMID:15297392
- PMID:15542781
- PMID:15637766
- PMID:15744590
- PMID:16001951
- PMID:16041610
- PMID:16080557
- PMID:16143373
- PMID:16149285
- PMID:16317298
- PMID:16500746
- PMID:16555971
- PMID:16584929
- PMID:16807461
- PMID:16807463
- PMID:16894289
- PMID:16905983
- PMID:17101674
- PMID:17296311
- PMID:17296587
- PMID:17347561
- PMID:17429628
- PMID:17460420
- PMID:17602464
- PMID:17639396
- PMID:17887663
- PMID:17939651
- PMID:17941128
- PMID:17987263
- PMID:18035967
- PMID:18050344
- PMID:18086345
- PMID:18166944
- PMID:18186604
- PMID:18257544
- PMID:18348652
- PMID:18773046
- PMID:18789834
- PMID:18819792
- PMID:18981552
- PMID:19034448
- PMID:19177022
- PMID:19399788
- PMID:19839926
- PMID:19879060
- PMID:22763439
- PMID:28594276
- PMID:28608357
- PMID:28912244
- Patent:EP1939198
- Patent:EP2108368
- Patent:EP2275135
- Patent:GB2136425
- Patent:US2009124797
- Patent:US2010111852
- Patent:US4808614
- Reaxys:5382060
- Wikipedia:Gemcitabine
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
- inverse has_part
-
Phenotype
Phenotype resulting from gemcitabine
Phenotype where environments contain gemcitabine
Phenotype modified by environments containing gemcitabine
Human Disease / Model Data