PD-146176

Term ID

CHEBI:173098

Synonyms

6,11-dihydro[1]benzothiopyrano[4,3-b]indole
6,11-dihydrothiochromeno[4,3-b]indole
PD 146176
PD146176

Definition

An organic heterotetracyclic compound that is 1H-indole which is ortho-fused to a 2H-1-benzothiopyran group at positions 2-3. It is an inhibitor of 15-lipoxygenase that limits atherosclerotic lesion development in rabbits.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: organic heterotetracyclic compound organonitrogen heterocyclic compound organosulfur heterocyclic compound

organic heterotetracyclic compound organonitrogen heterocyclic compound organosulfur heterocyclic compound Show first 5 Terms
has_role: antiatherogenic agent EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor ferroptosis inhibitor

antiatherogenic agent EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor ferroptosis inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from PD-146176

Phenotype where environments contain PD-146176

Phenotype modified by environments containing PD-146176

Human Disease Model