Search Ontology:
ChEBI
bictegravir
- Term ID
- CHEBI:172943
- Synonyms
-
- (2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
- bictegravir
- bictegravirum
- GS-9883
- GS-9883-01
- Definition
- A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2R,5S,13aR)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid with the amino group of 2,4,6-trifluorobenzylamine. It is a second-generation integrase strand transfer inhibitor (INSTI) and used (as its sodium salt) for the treatment of HIV-1.
- References
-
- CAS:1611493-60-7
- Chemspider:44208822
- DrugBank:DB11799
- KEGG:D10909
- PDBeChem:KLQ
- PMCID:PMC7776652
- PMCID:PMC7777652
- PMID:27645238
- PMID:28196003
- PMID:29746268
- PMID:31840682
- PMID:32001521
- PMID:32001525
- PMID:32041480
- PMID:32623580
- PMID:32668455
- PMID:32693738
- PMID:32796211
- PMID:32862660
- PMID:32868324
- PMID:32945851
- PMID:33105171
- PMID:33202006
- PMID:33280486
- PMID:33390993
- PMID:33511239
- PMID:33521960
- PMID:33526487
- PMID:33626178
- PMID:33649107
- PMID:33686573
- PMID:33729482
- PMID:33880558
- PMID:33977505
- Wikipedia:Bictegravir
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
- inverse is_conjugate_base_of
-
- is_conjugate_acid_of
-
Show first 5 Terms
Phenotype
Phenotype resulting from bictegravir
Phenotype where environments contain bictegravir
Phenotype modified by environments containing bictegravir
Human Disease Model