L-proline

Term ID

CHEBI:17203

Synonyms

(-)-(S)-proline
(-)-2-pyrrolidinecarboxylic acid
(-)-proline
(2S)-pyrrolidine-2-carboxylic acid
(S)-2-carboxypyrrolidine
(S)-2-pyrrolidinecarboxylic acid
(S)-pyrrolidine-2-carboxylic acid
2-Pyrrolidinecarboxylic acid
L-(-)-proline
L-alpha-pyrrolidinecarboxylic acid
L-Prolin
L-proline
L-pyrrolidine-2-carboxylic acid
P
prolina
PROLINE
prolinum

Definition

Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: glutamine family amino acid L-alpha-amino acid proline proteinogenic amino acid

glutamine family amino acid L-alpha-amino acid proline proteinogenic amino acid Show first 5 Terms
has subtype: L-proline-d7

L-proline-d7 Show first 5 Terms
has_role: algal metabolite compatible osmolytes Escherichia coli metabolite micronutrient mouse metabolite ... Show All 7 Terms

algal metabolite compatible osmolytes Escherichia coli metabolite micronutrient mouse metabolite nutraceutical Saccharomyces cerevisiae metabolite Show first 5 Terms
inverse has_functional_parent: (2S,5S)-5-amino-4-oxo-1,2,4,5,6,7-hexahydroazepino[3,2,1-hi]indole-2-carboxylic acid (E)-nesocodin (alcohol-form) zwitterion (E)-nesocodin (oxo-form) zwitterion acromelic acid A Ala-Ala-Pro ... Show All 69 Terms

(2S,5S)-5-amino-4-oxo-1,2,4,5,6,7-hexahydroazepino[3,2,1-hi]indole-2-carboxylic acid (E)-nesocodin (alcohol-form) zwitterion (E)-nesocodin (oxo-form) zwitterion acromelic acid A Ala-Ala-Pro Ala-Ala-Pro-Pro Ala-Asn-Asn-Pro Ala-Asn-Asp-Pro Ala-Asp-Pro Ala-Gln-Pro Ala-Gly-Pro Ala-Leu-Ala-Pro Ala-Leu-Thr-Pro Ala-Pro Ala-Thr-Ala-Pro Ala-Val-Asp-Pro Ala-Val-Pro-Pro Arg-Pro Arg-Trp-Pro Asn-Asn-Pro-Ser Asn-Gly-Pro-His Asn-Met-Gln-Pro Asn-Pro Asp-Gly-Pro Asp-Met-Thr-Pro Asp-Pro-Ser-Ser Asp-Val-Gly-Pro Asp-Val-Pro-Pro cyclo(L-His-L-Pro) Cys-Pro Gln-Leu-Leu-Pro Glu-Pro Gly-Arg-Pro Gly-Pro Gly-Pro-Hyp Ile-Leu-Pro L-proline derivative Leu-Gly-Pro Leu-Pro Leu-Pro-Tyr Lys-Thr-Pro-Pro maculosin Met-Pro notoamide Phe-Ala-Pro Phe-Pro-Pro Phe-Pro-Thr Pro-Arg Pro-Arg-Pro Pro-Cys Pro-Glu-Ile Pro-Hyp Pro-Met Pro-Pro Pro-Pro-Pro Pro-Ser Pro-Thr Pro-Trp-Val-Gly Pro-Val-Gly-Pro Pro-Val-Val-Pro Ser-Asp-Lys-Pro Thr-Pro Thr-Pro-Pro Thr-Pro-Tyr Trp-Pro Tyr-Pro Val-Asn-Pro Val-Pro Val-Pro-Pro Show first 5 Terms
inverse has_part: royal jelly

royal jelly Show first 5 Terms
inverse is_conjugate_acid_of: L-prolinium

L-prolinium Show first 5 Terms
inverse is_conjugate_base_of: L-prolinate

L-prolinate Show first 5 Terms
inverse is_enantiomer_of: D-proline

D-proline Show first 5 Terms
inverse is_substituent_group_from: L-proline residue L-prolino group L-prolyl group

L-proline residue L-prolino group L-prolyl group Show first 5 Terms
inverse is_tautomer_of: L-proline zwitterion

L-proline zwitterion Show first 5 Terms
is_conjugate_acid_of: L-prolinate

L-prolinate Show first 5 Terms
is_conjugate_base_of: L-prolinium

L-prolinium Show first 5 Terms
is_enantiomer_of: D-proline

D-proline Show first 5 Terms
is_tautomer_of: L-proline zwitterion

L-proline zwitterion Show first 5 Terms

Phenotype

Phenotype resulting from L-proline

Phenotype where environments contain L-proline

Phenotype modified by environments containing L-proline

Human Disease Model