dutomycin

Term ID

CHEBI:171673

Synonyms

(2R,3S,6S)-6-{[(1R,4aS,12aR)-3-acetyl-2,4a,6,12a-tetrahydroxy-9-methoxy-11-methyl-4,5,7,10-tetraoxo-1,4,4a,5,7,10,12,12a-octahydrotetracen-1-yl]oxy}-2-methyltetrahydro-2H-pyran-3-yl 2,6-dideoxy-4-O-[(2Z,4R)-2,4-dimethylhept-2-enoyl]-3-C-methyl-alpha-L-xyl

Definition

An anthracycline antibiotic of formula C44H54O17 isolated from Streptomyces species. It directly binds to the human serine protease inhibitor B6 (SERPINB6), inducing autophagy and apoptosis.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: 1,4-benzoquinones anthracycline antibiotic carbohydrate-containing antibiotic carbopolycyclic compound disaccharide derivative ... Show All 10 Terms

1,4-benzoquinones anthracycline antibiotic carbohydrate-containing antibiotic carbopolycyclic compound disaccharide derivative enoate ester enol ether phenols tertiary alpha-hydroxy ketone Show first 5 Terms
has_role: antineoplastic agent apoptosis inducer autophagy inducer bacterial metabolite

antineoplastic agent apoptosis inducer autophagy inducer bacterial metabolite Show first 5 Terms

Phenotype

Phenotype resulting from dutomycin

Phenotype where environments contain dutomycin

Phenotype modified by environments containing dutomycin

Human Disease / Model Data