Search Ontology:
ChEBI
3-hydroxy-3-methylglutaric acid
- Term ID
- CHEBI:16831
- Synonyms
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- (S)-3-Hydroxy-3-methylglutaric acid
- (S)-Meglutol
- 3-HYDROXY-3-METHYL-GLUTARIC ACID
- 3-Hydroxy-3-methylpentanedioic acid
- beta-hydroxy-beta-methylglutaric acid
- Dicrotalic acid
- meglutol
- meglutolum
- Definition
- A dicarboxylic acid that is glutaric acid in which one of the two hydrogens at position 3 is substituted by a hydroxy group, while the other is substituted by a methyl group. It has been found to accumulate in urine of patients suffering from HMG-CoA lyase (3-hydroxy-3-methylglutaryl-CoA lyase, EC 4.1.3.4) deficiency. It occurs as a plant metabolite in Crotalaria dura.
- References
-
- CAS:503-49-1
- DrugBank:DB04377
- Drug_Central:1670
- HMDB:HMDB0000355
- KEGG:C03761
- KEGG:D04897
- KNApSAcK:C00001187
- MetaCyc:CPD-547
- PDBeChem:MAH
- PMID:10916782
- PMID:17941049
- PMID:3063529
- PMID:4717513
- PMID:6083597
- PMID:9658458
- Reaxys:1769194
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_functional_parent
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- has_role
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- inverse has_functional_parent
- inverse is_conjugate_base_of
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- is_conjugate_acid_of
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Phenotype
Phenotype resulting from 3-hydroxy-3-methylglutaric acid
Phenotype where environments contain 3-hydroxy-3-methylglutaric acid
Phenotype modified by environments containing 3-hydroxy-3-methylglutaric acid
Human Disease Model