Search Ontology:
ChEBI
brivanib
- Term ID
- CHEBI:167686
- Synonyms
-
- (2R)-1-({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)propan-2-ol
- (R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5- methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan- 2-ol
- BMS 540215
- BMS-540215
- BMS540215
- Definition
- A secondary alcohol resulting from the hydrolysis of the carboxylic ester group of brivanib alaninate. It is a dual VEGFR-2/FGFR-1 kinase inhibitor whose alanine prodrug, brivanib alaninate is currently under development as an oral agent for the treatment of cancer.
- References
-
- CAS:649735-46-6
- Chemspider:9409099
- DrugBank:DB11958
- KEGG:D09589
- PMID:16570908
- PMID:18288793
- PMID:19396600
- PMID:20671097
- PMID:21289073
- PMID:24780101
- PMID:30595557
- PMID:31270802
- PMID:31522033
- PMID:31633365
- Patent:WO2011044019
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
- inverse has_functional_parent
-
Phenotype
Phenotype resulting from brivanib
Phenotype where environments contain brivanib
Phenotype modified by environments containing brivanib
Human Disease Model