Search Ontology:
ChEBI
tesevatinib
- Term ID
- CHEBI:167674
- Synonyms
-
- 7-{[(3aR,5R,6aS)-2-methyl-octahydrocyclopenta[c]pyrrol-5-yl]methoxy}-N-(3,4-dichloro-2-fluorophenyl)-6-methoxyquinazolin-4-amine
- EXEL 7647
- EXEL-7647
- EXEL7647
- KD 019
- KD-019
- KD019
- N-(3,4-dichloro-2-fluorophenyl)-6-methoxy-7-{[(3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methoxy}quinazolin-4-amine
- tesevatinib
- tesevatinibum
- XL 647
- XL-647
- XL647
- Definition
- A member of the class of quinazolines that is quinazoline substituted by (3,4-dichloro-2-fluorophenyl)amino, methoxy, and [(3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methoxy groups at positions 4, 6 and 7, respectively. It is a multi-target tyrosine kinase inhibitor of EGFR, ErbB2, KDR, Flt4 and EphB4 and exhibits anti-cancer properties.
- References
-
- CAS:781613-23-8
- Chemspider:32699556
- DrugBank:DB11973
- KEGG:D11772
- PMID:17575237
- PMID:18413839
- PMID:18520300
- PMID:19362942
- PMID:22011666
- PMID:22173702
- PMID:22722787
- PMID:23411383
- PMID:28729967
- PMID:30030583
- PMID:31692482
- Wikipedia:Tesevatinib
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
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Phenotype
Phenotype resulting from tesevatinib
Phenotype where environments contain tesevatinib
Phenotype modified by environments containing tesevatinib
Human Disease / Model Data