Search Ontology:
ChEBI
SLM6071469
- Term ID
- CHEBI:167671
- Synonyms
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- (2S)-2-[3-[3-(trifluoromethyl)-4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carboximidamide
- (2S)-2-{3-[3-(trifluoromethyl)-4-{[4-(trifluoromethyl)benzyl]oxy}phenyl]-1,2,4-oxadiazol-5-yl}pyrrolidine-1-carboximidamide
- (S)-2-(3-(3-(trifluoromethyl)-4-((4-(trifluoromethyl)benzyl)oxy)phenyl)-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboximidamide
- SLM 6071469
- SLM-6071469
- Definition
- A 1,2,4-oxadiazole that is substituted by 3-(trifluoromethyl)-4-{[4-(trifluoromethyl)benzyl]oxy}phenyl and (2S)-1-carbamimidoylpyrrolidin-2-yl groups at positions 3 and 5, respectively. It is a potent inhibitor of sphingosine kinase 2 (SphK2) with Ki of 89 nM.
- References
-
- Chemspider:88298529
- PMID:31895563
- Patent:WO2017172989
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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Show first 5 Terms
Phenotype
Phenotype resulting from SLM6071469
Phenotype where environments contain SLM6071469
Phenotype modified by environments containing SLM6071469
Human Disease / Model Data