Search Ontology:
ChEBI
AZT-1152
- Term ID
- CHEBI:167636
- Synonyms
-
- 2-[ethyl(3-{[4-({5-[2-(3-fluoroanilino)-2-oxoethyl]-1H-pyrazol-3-yl}amino)quinazolin-7-yl]oxy}propyl)amino]ethyl dihydrogen phosphate
- AZD1152-HQPA dihydrogen phosphate
- AZD2811
- barasertib
- barasertibum
- INH-34
- Definition
- A dihydrogen phosphate prodrug of a pyrazoloquinazoline aurora kinase inhibitor AZD1152-hydroxyquinazoline pyrazol anilide(HQPA) and is converted rapidly to the active AZD1152-HQPA in plasma.
- References
-
- CAS:722543-31-9
- CAS:957881-03-7
- DrugBank:DB11747
- PMCID:PMC4108943
- PMID:21565405
- PMID:21626115
- PMID:21679421
- PMID:21976672
- PMID:22661287
- PMID:22864876
- PMID:23315030
- PMID:23557198
- PMID:23605952
- PMID:23763917
- PMID:24598913
- PMID:26637878
- PMID:26993175
- PMID:27069145
- PMID:27496133
- PMID:28292940
- PMID:29491065
- PMID:30540594
- PMID:30872381
- PMID:32968211
- Ontology
- ChEBI ( EBI )
- is a type of
- has_functional_parent
-
- has_role
-
Phenotype
Phenotype resulting from AZT-1152
Phenotype where environments contain AZT-1152
Phenotype modified by environments containing AZT-1152
Human Disease Model