Search Ontology:
ChEBI
fostriecin
- Term ID
- CHEBI:167004
- Synonyms
-
- (+)-fostriecin
- (1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-1-[(2R)-6-oxo-3,6-dihydro-2H-pyran-2-yl]trideca-1,7,9,11-tetraen-4-yl dihydrogen phosphate
- (6R)-5,6-dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one
- antibiotic CI 920
- antibiotic CL 1565A
- CI 920
- CI-920
- CL 1565A
- CL-1565A
- fostriecin
- fostriecina
- fostriecine
- fostriecinum
- PD 110,161
- PD 110161
- PD-110,161
- phosphotrienin
- Definition
- A structurally unique, naturally-occurring phosphate monoester isolated from the soil bacterium Streptomyces pulveraceus. It inhibits DNA topoisomerase II as well as several protein phosphatase including PP2A and PPA4, and exhibits potent antitumor activity against several cancer cell lines.
- References
-
- CAS:87810-56-8
- Chemspider:4510160
- KNApSAcK:C00018551
- PMID:11457179
- PMID:12119701
- PMID:12369868
- PMID:12489943
- PMID:12837094
- PMID:16316259
- PMID:19592665
- PMID:19902969
- PMID:20645347
- PMID:20687585
- PMID:23352138
- PMID:23586868
- PMID:23671329
- PMID:28027648
- PMID:28090813
- PMID:31584287
- PMID:33184589
- PMID:9738645
- Wikipedia:Fostriecin
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
- has_role
-
Show All 7 Terms
Show first 5 Terms
Phenotype
Phenotype resulting from fostriecin
Phenotype where environments contain fostriecin
Phenotype modified by environments containing fostriecin
Human Disease Model