EG00229

Term ID

CHEBI:166820

Synonyms

EG 00229
EG-00229
N(2)-({3-[(2,1,3-benzothiadiazol-4-ylsulfonyl)amino]thiophen-2-yl}carbonyl)-L-arginine
N(2)-[[3-[(2,1,3-benzothiadiazol-4-ylsulfonyl)amino]-2-thienyl]carbonyl]-L-arginine

Definition

A member of the class of thiophenes that is thiophene substituted by a carbonyl-L-arginine and (2,1,3-benzothiadiazole-4-sulfonyl)amino groups at positions 2 and 3. It is an inhibitor of the neuropilin-1 and VEGF-A interaction and a potential anti-cancer agent.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: benzothiadiazole dicarboxylic acid monoamide L-arginine derivative secondary carboxamide sulfonamide ... Show All 6 Terms

benzothiadiazole dicarboxylic acid monoamide L-arginine derivative secondary carboxamide sulfonamide thiophenes Show first 5 Terms
has_role: angiogenesis inhibitor antineoplastic agent neuropilin receptor antagonist

angiogenesis inhibitor antineoplastic agent neuropilin receptor antagonist Show first 5 Terms

Phenotype

Phenotype resulting from EG00229

Phenotype where environments contain EG00229

Phenotype modified by environments containing EG00229

Human Disease / Model Data