N(7)-methyl-GpppA

Term ID

CHEBI:157762

Synonyms

2-amino-9-[(2R,3R,4S,5R)-5-({[(R)-{[(R)-{[(S)-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxytetrahydrofuran-2-yl]-7-methyl-6
2-amino-9-[(2R,3R,4S,5R)-5-({[{[{[{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxytetrahydrofuran-2-yl]-7-methyl-6-oxo-6,9-dih
7-methyl-GpppA
[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-7-ium-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl] hydrogen phosphate
m(7)-GpppA
m(7)GP3A
m(7)GpppA
N(7)-MeGpppA
P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate

Definition

A guanosine 5'-phosphate that is 7-methyl-GTP(1+) in which the hydroxy group of the terminal phosphate is substituted by an adenosyl group. It is a cap analog that can be incorporated into mRNA.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: adenosine 5'-phosphate guanosine 5'-phosphate purine ribonucleoside 5'-triphosphate

adenosine 5'-phosphate guanosine 5'-phosphate purine ribonucleoside 5'-triphosphate Show first 5 Terms
has_functional_parent: 7-methyl-GTP(1+)

7-methyl-GTP(1+) Show first 5 Terms
inverse is_conjugate_base_of: (N(7)-methyl 5'-triphospho-guanosine)-adenosine(2-)

(N(7)-methyl 5'-triphospho-guanosine)-adenosine(2-) Show first 5 Terms
is_conjugate_acid_of: (N(7)-methyl 5'-triphospho-guanosine)-adenosine(2-)

(N(7)-methyl 5'-triphospho-guanosine)-adenosine(2-) Show first 5 Terms

Phenotype

Phenotype resulting from N(7)-methyl-GpppA

Phenotype where environments contain N(7)-methyl-GpppA

Phenotype modified by environments containing N(7)-methyl-GpppA

Human Disease Model