10-formyltetrahydrofolic acid

Term ID

CHEBI:15637

Synonyms

10-formyl-(6RS)-tetrahydrofolic acid
10-formyl-5,6,7,8-tetrahydrofolic acid
10-formyl-THF
10-Formyltetrahydrofolate
10-formyltetrahydropteroylglutamic acid
10-FTHF
10-HCO-H4folic acid
N(10)-formyl-5,6,7,8-tetrahydrofolic acid
N(10)-formyl-THF
N(10)-formyltetrahydrofolic acid
N-(10-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl](formyl)amino}benzoyl)-L-glutamic acid

Definition

A form of tetrahydrofolate that acts as a donor of formyl groups in anabolism. In these reactions 10-formyltetrahydrofolic acid is used as a substrate in formyltransferase reactions, which is important in purine biosynthesis.

References

Beilstein:101559
CAS:2800-34-2
FooDB:FDB022345
HMDB:HMDB0000972
KEGG:C00234
KNApSAcK:C00007251
PMID:1095054
PMID:13336106
PMID:13672973
PMID:9833324

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: formyltetrahydrofolic acid

formyltetrahydrofolic acid Show first 5 Terms
has subtype: (6R)-10-formyltetrahydrofolic acid (6S)-10-formyltetrahydrofolic acid

(6R)-10-formyltetrahydrofolic acid (6S)-10-formyltetrahydrofolic acid Show first 5 Terms
has_role: Escherichia coli metabolite mouse metabolite

Escherichia coli metabolite mouse metabolite Show first 5 Terms
inverse has_functional_parent: 10-formyltetrahydrofolyl polyglutamate macromolecule

10-formyltetrahydrofolyl polyglutamate macromolecule Show first 5 Terms
inverse is_conjugate_base_of: 10-formyltetrahydrofolate(2-)

10-formyltetrahydrofolate(2-) Show first 5 Terms
is_conjugate_acid_of: 10-formyltetrahydrofolate(2-)

10-formyltetrahydrofolate(2-) Show first 5 Terms

Phenotype

Phenotype resulting from 10-formyltetrahydrofolic acid

Phenotype where environments contain 10-formyltetrahydrofolic acid

Phenotype modified by environments containing 10-formyltetrahydrofolic acid

Human Disease Model