Search Ontology:
ChEBI

enasidenib

Term ID
CHEBI:145374
Synonyms
  • 2-methyl-1-[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol
  • AG 221
  • AG-221
  • CC-90007
  • enasidenib
  • enasidenibum
  • Idhifa
Definition
A 1,3,5-triazine which is substituted by (2-hydroxy-2-methylpropyl)nitrilo, 6-(trifluoromethyl)pyridin-2-yl and [2-(trifluoromethyl)pyridin-4-yl]nitrilo groups at positions 2,4 and 6, respectively. It is an isocitrate dehydrogenase-2 (IDH2) inhibitor which has been approved for the treatment of adults with relapsed or refractory acute myeloid leukaemia (AML).
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from enasidenib
Phenotype where environments contain enasidenib
Phenotype modified by environments containing enasidenib
Human Disease Model
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