PF-956980

Term ID

CHEBI:144672

Synonyms

PF 956980
PF-956980
PF956980
PFE-PKIS 8
{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}(pyrrolidin-1-yl)methanone

Definition

A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted at position 4 by a methyl[(3R,4R)-4-methyl-1-(pyrrolidin-1-ylcarbonyl)piperidin-3-yl]nitrilo group. It is a potent JAK3-selective chemical probe.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: N-acylpiperidine N-acylpyrrolidine pyrrolopyrimidine tertiary amino compound

N-acylpiperidine N-acylpyrrolidine pyrrolopyrimidine tertiary amino compound Show first 5 Terms
has_role: EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor

EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from PF-956980

Phenotype where environments contain PF-956980

Phenotype modified by environments containing PF-956980

Human Disease / Model Data