LDC4297

Term ID

CHEBI:144671

Synonyms

2-(piperidin-3-yloxy)-8-(propan-2-yl)-N-[2-(1H-pyrazol-1-yl)benzyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine
2-[(piperidin-3-yl)oxy]-8-(propan-2-yl)-N-{[2-(1H-pyrazol-1-yl)phenyl]methyl}pyrazolo[1,5-a][1,3,5]triazin-4-amine
8-(1-methylethyl)-2-(3-piperidinyloxy)-N-[[2-(1H-pyrazol-1-yl)phenyl]methyl]-pyrazolo[1,5-a]-1,3,5-triazin-4-amine
LCD044297
LDC 4297
LDC-4297

Definition

A pyrazolotriazine that is pyrazolo[1,5-a][1,3,5]triazine substituted by a piperidin-3-yloxy group, [2-(1H-pyrazol-1-yl)benzyl]nitrilo group and an isopropyl group at positions 2, 4 and 8 respectively. It is a potent and selective CDK7 inhibitor and exhibits antiviral activity.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether piperidines pyrazoles pyrazolotriazine secondary amino compound

aromatic ether piperidines pyrazoles pyrazolotriazine secondary amino compound Show first 5 Terms
has_role: antineoplastic agent antiviral agent apoptosis inducer EC 2.7.11.22 (cyclin-dependent kinase) inhibitor

antineoplastic agent antiviral agent apoptosis inducer EC 2.7.11.22 (cyclin-dependent kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from LDC4297

Phenotype where environments contain LDC4297

Phenotype modified by environments containing LDC4297

Human Disease / Model Data