(R)-DRF053

Term ID

CHEBI:142838

Synonyms

(2R)-2-({9-isopropyl-6-[3-(pyridin-2-yl)anilino]-9H-purin-2-yl}amino)butan-1-ol

Definition

A member of the class of 2,6-diaminopurines that is 2,6-diamiopurine which is substituted by an isopropyl group at position 9 and in which the amino groups at positions 2 and 6 are substituted by a 1-hydroxybutan-2-yl and 3-(pyridin-2-yl)phenyl groups, respectively (the R enantiomer). A cyclin dependent kinase inhibitor, widely used as its hydrochloride hydrate.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: 2,6-diaminopurines phenylpyridine primary alcohol secondary amino compound

2,6-diaminopurines phenylpyridine primary alcohol secondary amino compound Show first 5 Terms
has_role: EC 2.7.11.22 (cyclin-dependent kinase) inhibitor

EC 2.7.11.22 (cyclin-dependent kinase) inhibitor Show first 5 Terms
inverse has_part: (R)-DRF053 hydrochloride hydrate

(R)-DRF053 hydrochloride hydrate Show first 5 Terms

Phenotype

Phenotype resulting from (R)-DRF053

Phenotype where environments contain (R)-DRF053

Phenotype modified by environments containing (R)-DRF053

Human Disease / Model Data