Search Ontology:
ChEBI

CHIC-35

Term ID
CHEBI:142489
Synonyms
  • (6S)-2-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxamide
  • Compound (S)-35
  • SIRT1 Inhibitor IV, (S)-35
Definition
An organic heterotricyclic compound resulting from the formal fusion of the 2-3 bond of 5-chloroindole with the 2-3 bond of cycloheptanecarboxamide (the S enantiomer). It is a potent, cell-permeable, metabolically stable and selective inhibitor of the deacetylase SIRT1.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from CHIC-35
Phenotype where environments contain CHIC-35
Phenotype modified by environments containing CHIC-35
Human Disease Model