Search Ontology:
ChEBI
CHIC-35
- Term ID
- CHEBI:142489
- Synonyms
-
- (6S)-2-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxamide
- Compound (S)-35
- SIRT1 Inhibitor IV, (S)-35
- Definition
- An organic heterotricyclic compound resulting from the formal fusion of the 2-3 bond of 5-chloroindole with the 2-3 bond of cycloheptanecarboxamide (the S enantiomer). It is a potent, cell-permeable, metabolically stable and selective inhibitor of the deacetylase SIRT1.
- References
-
- CAS:848193-72-6
- PMID:16335928
- PMID:21699209
- PMID:23499872
- PMID:26792944
- Reaxys:10274604
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from CHIC-35
Phenotype where environments contain CHIC-35
Phenotype modified by environments containing CHIC-35
Human Disease / Model Data