Search Ontology:
ChEBI

tyloxapol

Term ID
CHEBI:141517
Synonyms
  • 4-(1,1,2,2-tetramethylbutyl)phenol polyer with formaldehyde and oxirane
  • Alevaire
  • oxyethylated tertiary octylphenol formaldehyde polymer
  • p-(1,1,3,3-tetramethylbutyl)phenol polymer with ethylene oxide and formaldehyde
  • p-isooctylpolyoxyethylenenphenol formaldehyde polymer
  • Superinone
  • tiloxapol
  • Triton A-20
  • Triton WR-1339
  • tyloxapol
  • tyloxapolum
  • tyloxypal
Definition
A polymeric compound resulting from the reaction of 4-(1,1,3,3-tetramethylbutyl)phenol with formaldehyde to give a chain in which 6-8 molecules are linked together by CH2 groups ortho to the phenolic hydroxy groups, which have then undergone reaction with oxirane to give polyoxyethyleneoxy moieties, Ar(OCH2CH2)xOH, where x = 8-10. A nonionic liquic polymer, it inhibits lipoprotein lipase and hence clearance of triglyceride from the plasma, so is used to induce hyperlipidaemia in test animals. Also used as a surfactant to aid liquefaction and removal of mucus- and pus-containing bronchopulmonary secretions.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from tyloxapol
Phenotype where environments contain tyloxapol
Phenotype modified by environments containing tyloxapol
Human Disease Model
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