1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea

Term ID

CHEBI:140936

Synonyms

1-(1-methyl-1H-indol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea
3-(3-methyl-1,2-thiazol-5-yl)-1-(1-methylindol-5-yl)urea
N-(1-methyl-1H-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea
N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea
SB 204741
SB-204741
SB204741

Definition

A member of ther class of ureas that is urea in which a hydrogen attached to one of the nitrogens has been replaced by an N-methylindol-5-yl group, while a hydrogen attached to the other nitrogen has been replaced by a 3-methyl-1,2-thiazol-5-yl group. It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor.

References

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea

Phenotype where environments contain 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea

Phenotype modified by environments containing 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea

Human Disease Model